GB virus type C: a beneficial infection?
نویسندگان
چکیده
منابع مشابه
GB virus type C infection polarizes T-cell cytokine gene expression toward a Th1 cytokine profile via NS5A protein expression.
Human immunodeficiency virus (HIV) disease progression is associated with a helper T cell 1 (Th1) to helper T cell 2 (Th2) cytokine profile switch. Persistent GB virus type C (GBV-C) infection is associated with survival and a serum Th1 cytokine profile in HIV-infected individuals. We found that GBV-C infection increased gene expression of Th1 cytokines and decreased Th2 cytokine expression in ...
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متن کاملGB Virus Type C (HGV) and Human Immunodeficiency Virus (HIV) Co-Infection: Incidence and Impact on Survival in a Cohort of HIV-infected Transfusion Recipients
1 1. What we know about GB virus type C (Hepatitis G virus) 1 1.1. Molecular structure 1 1.2. History and distribution 1 1.3. Routes of transmission 2 1.4. Prevalence of GBV-C infection 2 1.4.1. Healthy blood donors 2 1.4.2. High risk populations 3 1.5. GBV-C detection methods 3 1.6. Natural history of GBV-C infection in humans 4 1.6.1. GBV-C and HIV co-infection 4 1.6.2. Biological mechanism o...
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BACKGROUND Coinfection with the flavivirus GB virus C (GBV-C) is frequent in patients suffering from HIV type-1 (HIV-1) infection because of shared routes of transmission. GBV-C coinfection has been proposed to exert a beneficial influence on HIV-1 infection. In vitro studies demonstrated down-regulation of C-C chemokine receptor type 5 (CCR5) as a potential mechanism by which GBV-C modulates H...
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BACKGROUND The picture that has emerged from studies investigating HIV infected people with GBV-C viremia is that they have lower plasma HIV viral loads in comparison with HIV-positive people who did not have the GBV-C viremia. OBJECTIVES Since GBV-C HIV coinfection has not been studied in Iran, we have designed a survey to study the outcomes of GBV-C infection on HIV infected individuals. ...
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عنوان ژورنال:
- Journal of clinical microbiology
دوره 42 9 شماره
صفحات -
تاریخ انتشار 2004